CLINICAL RESEARCH
Monument Health

CLINICAL RESEARCH

Clinical trials are research studies conducted with patients to find effective ways to prevent, detect, diagnose and treat a variety of conditions. They are also used to study the psychological impact of different conditions and help improve patient comfort and quality of life.

To enroll in a trial, speak to your doctor or contact Monument Health Clinical Research at 605-755-4326 or research@monument.health.

Clinical Trials

    • ACCRU GI-2008 – A Phase II Randomized Study of Atezolizumab plus Multi-Kinase Inhibitor Versus Multi-Kinase Inhibitor Alone in Subjects with Unresectable, Advanced Hepatocellular Carcinoma Who Previously Received Atezolizumab and Bevacizumab.

    • ASTRIDE – Randomized, Open-label Study of HLX10 plus Chemotherapy (CarboplatinEtoposide) in comparison with Atezolizumab plus Chemotherapy in Previously Untreated US Patients with Extensive Stage Small Cell Lung Cancer (ES-SCLC).

    • LoTam – LoTam: A Randomized, Phase III Clinical Trial of Low-Dose Tamoxifen for Selected Patients with Molecular Low-Risk Early-Stage Breast Cancer.

    • LUNGMAP – A Master Protocol to Evaluate Biomarker-Driven Therapies and Immunotherapies in Previously-Treated Non-Small Cell Lung Cancer (LUNG-MAP Screening Study)

    • S2012 – Randomized Phase II/III Trial of First Line Platinum/Etoposide with or Without Atezolizumab (NSC#783608) in Patients with Poorly Differentiated Extrapulmonary Small Cell Neuroendocrine Carcinomas (NEC).

    • S2312 – Combining Cabazitaxel and Carboplatin to Treat Castrate-Resistant Prostate Cancer.

    • MAGICAL BTK – Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in the Treatment of Below the Knee Arterial Disease

    • SOS-AMI – Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

    • LIBREXIA-ACS – A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome

    • Dal-GenE-2 – Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

    • ARTEMIS – A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

    • ACCLAIM Lp(a) – A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a)

    • EASi-HF – A Study to Test Whether BI 690517 in Combination With Empagliflozin Helps People With Heart Failure
    • AZURE LDL – A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event
    • AZURE Outcomes – A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
    • MARITIME-CV – Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
    • VICTORION-INTERVENTION – Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

    • ALLAY-HF – Prospective, multicenter, randomized, sham-controlled, double blinded, adaptive study designed to evaluate the safety and efficacy of a percutaneously created interatrial shunt using the Alleviant ALV1 System in patients with HFpEF/HFmrEF
    • ALLAY-HFrEF – Prospective, multicenter, randomized, sham-controlled, double blind (patient and observer), study designed to evaluate the safety and efficacy of a percutaneously created interatrial shunt using the Alleviant ALV1 System in patients with HFrEF

    • HERMES – A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
    • COMET-HF – Study with Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure with Severely Reduced Ejection Fraction
    • BalanceD-HF – Study to Evaluate the Effect of Balcinrenone/​Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
    • MARITIME HF – Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Clinical Research

We conduct clinical and specialty research in a wide variety of areas: treatment, prevention, diagnostic and screening, pharmaceutical trials, cardiac device trials and symptom management trials.

Volunteering for a research study means you will help develop medical therapies and treatments for the future. If are interested in participating in clinical trials, talk to your physician or contact Clinical Research at 605-755-4326.

Email: research@monument.health.

 

SPECIALTY RESEARCH

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