SPECIALTY RESEARCH
CARDIOLOGY RESEARCH
Heart and Vascular Institute physicians and surgeons have participated in over 250 clinical trials (phase 1-4) in the past 20 years and collectively contributed over 10,000 patient years of clinical data.
There are currently 45 active trials and over 600 active participant volunteers.
Call 605-755-4326 if you are interested in any of our clinical trials.
For more information on cardiology at Monument Health click here.
CANCER CARE RESEARCH
The Cancer Care Institute conducts clinical trials (research studies) with patients to prevent, detect, diagnose, and treat cancers and to study the psychological impact of cancer, which helps improve patient comfort and quality of life.
Patients who take part in clinical trials have a unique opportunity to receive the most advanced care available — either with a new treatment or with the best standard therapy.
If you are interested in cancer care clinical trials, call 605-755-2370 or speak with your physician.
For more information on cancer care at Monument Health click here.
CLINICAL RESEARCH
Monument Health Clinical Research (MHCR) provides research services for inpatient, outpatient, surgical services and rehab for Family Medicine, Pediatric Endocrinology, Endocrinology, Rheumatology, Infectious Disease and Nephrology.
For more information, contact Monument Health Clinical Research at (605) 755-4326.
Active Clinical Trials
Heart Failure Trials
- ALLAY-HF – Prospective, multicenter, randomized, sham-controlled, double blinded, adaptive study designed to evaluate the safety and efficacy of a percutaneously created interatrial shunt using the Alleviant ALV1 System in patients with HFpEF/HFmrEF
- HERMES – A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
- COMET-HF – Study with Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure with Severely Reduced Ejection Fraction
- BalanceD-HF – Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Device Trials
General Cardiology
- SOS-AMI – Selatogrel Outcome Study in Suspected Acute Myocardial Infarction
- LIBREXIA-ACS – A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
- CORALreef Lipids – A Study of MK-0616 (Oral PCSK9 Inhibitor) in Adults with Hypercholesterolemia (MK-0616-013)
- CORALreef Outcomes – MK-0616 (Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015)
- Dal-GenE-2 – Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
- ARTEMIS – A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
- ACCLAIM Lp(a) – A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a)
- CYCLE-1 – A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction
- CYCLE-2 – Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction
- EASi-HF – A Study to Test Whether BI 690517 in Combination With Empagliflozin Helps People With Heart Failure
Clinical trials are research studies conducted with patients to find effective ways to prevent, detect, diagnose and treat a variety of conditions. They are also used to study the psychological impact of different conditions and help improve patient comfort and quality of life.
To enroll in a trial, speak to your doctor or contact Monument Health Clinical Research at 605-755-4326 or email research@monument.health.